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Given its essential role in the detoxification of lipid hydroperoxides, and its overexpression in most of myeloid malignancies, GPX4 inhibition has emerged as a promising therapeutic strategy to specifically trigger ferroptosis and eradicate myeloid leukemia cells

One hypothesis considers this phenomenon to be attributable to an abundance of anti-inflammatory species, such as Faecalibacterium prausnitzii , which promotes sequestration of regulatory T cells within the intestine

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Cancer Epidemiol Biomarkers Prev 3:310 Qiao X, Li G, Zhang J et al (2022) Urinary analysis reveals high Alternaria mycotoxins exposure in the general population from Beijing, China