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After a treatment period of 3 months, to test the effectiveness of treatment as part of usual clinical care, vitamin B12 levels, activity meter, and questionnaires were repeated

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These findings indicate that adenosinergic metabolism remains active during DARA therapy, likely sustained by reduced CD38 expression due to antibody_driven internalization or microvesicle (MV) release, together with adenosine deaminase (ADA) -mediated ADO degradation

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With SIBO, B12 made by the bacteria in the large intestine can migrate to the small intestine and get picked up by B12 transporters