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I treat it as a tool with a strong mechanistic rationale, an excellent safety signal in the studies we have, and a body of evidence that's still maturing on the human side

doi: 10.3390/md7010024 35 HuangB.LiuX.FryJ

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It addresses the coupling of systemic nutritional states (wellfed versus fasting), hepatic filtering, and a tumor-specific firstpass through the stroma with the ways in which cancers struggle to maintain fuel supply despite constraints

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