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Co-administration of CDK9-PROTAC (GT-02897) with all-trans retinoic acid (ATRA) leads to synergistic attenuation of tumor growth in vitro and in xenograft models, providing a potential translational treatment for complete eradication of CTCL

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Because it influences so many fundamental biological pathways, its introduction into a system that is already compromised can have significant, sometimes catastrophic, consequences

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In contrast, elevation in GSH pool, reported in some metal-exposed plants has been considered as a strategy to detoxify/tolerate metals(Cd)-accrued consequences either by direct binding or by synthesis of PCs (Cnovas et al., 2007

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