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Description

Second-generation CARs incorporate a single co-stimulatory signal, such as CD28 or 4-1BB, whereas third-generation CARs combine multiple co-stimulatory motifs to further amplify immune responses

Problems Endocrinol

Inhibitory neurotransmission, plasticity and aging in the mammalian central auditory system

Am J Transl Res 11(9):53245331 Mueller BK, Mack H, Teusch N (2005) Rho kinase, a promising drug target for neurological disorders

Associations do not necessarily mean the cause-effect relationship

There is preliminary evidence that non-pharmacological therapies used in mental disorders like ECT are able to induce changes in gut microbiota [241, 242]