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Nevertheless, several difficulties are encountered in the implementation of these treatment methods, such as the requirements of technical expertise in purifying small molecules, the dosage of small purified molecules to treatment, whether the harmful genes among the opportunistic pathogenic bacteria can be completely knocked out, and whether knocking out these bacterial genes have potential risks implications to the host health

Zhou W, Gui M, Zhu M, Long Z, Huang L, Zhou J, He L, Zhong K (2014) Nicotinamide N-methyltransferase is overexpressed in prostate cancer and correlates with prolonged progression-free and overall survival times

For any supplement brand to clinically demonstrate that its BPC-157 product is "most effective," the standard would generally require independent, head-to-head comparative studies against competing products, measuring defined endpoints in human subjects

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Journal of Clinical and Aesthetic Dermatology, 2(3), 38