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Conclusion: While A1AT PI*MZ variant significantly increases the risk of liver related events in patients with non-lean NAFLD, it interestingly, did not seem to significantly increase the risk of developing hepatic events in patients with lean-NAFLD

Iron accumulation in senescent cells is coupled with impaired ferritinophagy and inhibition of ferroptosis

Neutralizing free radicals and aiding detoxification is crucial in achieving and maintaining clear, even-toned skin

PRLMs not only represent promising molecular targets for inflammation resolutionbased therapies in hypertension but also hold potential for advancing the precision management of patients with hypertension

Together, these intriguing findings demonstrate that RSL3 can effectively induce DNA damage, impair DNA damage repair response, and trigger autophagy in thyroid cancer cells by inhibiting GPX4

1700262, 2017 [50] I