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On the other hand, increasing evidence suggests the involvements of trans-synaptic deteriorations of post-retinal structures along the central visual pathway in glaucoma (Gupta et al., 2006), yet the majority of studies focus only on subjects with glaucoma approaching advanced stages (Lawlor et al., 2018)

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For instance, a single hydrogen bond structure exhibits relatively weak molecular recognition and self-assembly capabilities in aqueous solutions, as its hydrogen bond interactions are prone to dissociate in water [111]