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Sener G, Paskaloglu K, Satiroglu H, Alican I, Kamaz A, Sakarcan AJJocp

To further confirm these findings, we performed Western blot and qRT-PCR analyses, which showed that both protein and mRNA levels of CPT1A were downregulated in STC-induced SAP models, both in vitro and in vivo (Figures 1DI)

This pathological process is further amplified through a vicious cycle wherein excess ammonia induces inducible NOS (iNOS)-mediated GS nitration (Cudre-Cung et al

We also discuss how the outcomes associated with different timing of therapeutic intervention are contributing to our understanding of the biology and pathogenesis of SMA