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doi: 10.1016/j.micres.2018.09.011 36 SouliotisVLVlachogiannisNIPappaMArgyriouANtourosPASfikakisPP

As the syndrome persists for weeks, discomfort in sleep, poor concentration, and depression become evident

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Reasons for inhaled GSH's effectiveness include its role as a potent antioxidant, and possibly improved oxygenation and host defenses

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GSH can also serve as a substrate for S-glutathionylation of proteins in the presence of small redox enzyme glutaredoxins (GRX), which also utilizes GSH as a cofactor ( Figure 1 )