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For instance, ubiquitination can lead to NRF2 degradation and reduced antioxidant activity, while deubiquitination enhances its stability and function

By reducing oxidative stress, glutathione helps slow down the aging process, diminishing the appearance of fine lines, wrinkles, and age spots

During this process, oxidized glutathione is converted back to its reduced form by the enzyme glutathione reductase and nicotinamide adenine dinucleotide phosphate (NADPH)

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Mammalian GGT is a heterodimeric type-II transmembrane glycoprotein that is translated as a single precursor and post-translationally processed into a dimeric form by autocatalytic limited proteolysis [76]

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