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Additionally, IL-6 acts not only as a pro-inflammatory mediator during this initial response but also helps modulate anti-inflammatory factors such as IL-10, maintaining immune homeostasis after exercise (79)

J Pharmacol Exp Ther 290 (1): 136-45 (1999)

Being ubiquitously expressed in different cell types and tissues it is retained in inactive form in the cytoplasm by complexing with its negative regulator, Keap1

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