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Various hematological parameters, including WBC, hemoglobin, and platelet levels, showed no significant changes (31)

The siRNA duplex solution was prepared and diluted to 2.4 mg/ml according to the manufacturers instructions

However, pegylated uricases are highly immunogenic resulting in the formation of anti-drug antibodies (ADAs) in ~90% of patients 2,7 , correlating with the loss of therapeutic benefit and increased infusion reactions 2

Although miR-214 alone had little effect on the cell viability of AML12 cells (Fig

Bei oraler Einnahme sind Glutaminpeptide im Bezug auf die Erhhung der Blut- und Gewebewerte effektiver als Glutamin in der freien Aminosureform

Binding of ubiquitinated proteins to USP14 causes 20S proteasome gate opening, thereby linking proteasomal deubiquitination to protein degradation (Peth et al., 2009)