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More importantly, by simultaneously activating both a chemotherapeutic prodrug and an immunoadjuvant prodrug, the strategy maximizes therapeutic efficacy while nearly eliminating systemic side effects-achieving safe and efficient in situ vaccination. Porphyrin-based COFs represent excellent nanoplatforms for PDT and PTT

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A model opens the new insight for the L-lactate role in the brain and perfectly elaborates the mechanism of L-lactate how to serve as energy substrates

However, over-nourished, sedentary modern lifestyles disrupt this system and can cause serious medical problems, which include metabolic syndrome, obesity, type 2 diabetes mellitus (T2DM), and cardiovascular disease

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