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Neuroprotective effects of urate are mediated by augmenting astrocytic glutathione synthesis and release

ROS build up in stressed mitochondria has been proposed as a major player at the origin of NIHL (Bttger and Schacht, Figure 2)

doi: 10.1192/bjp.211.2.117

Previous studies, involving stocks of barley, showed that exogenous GSH reduced the absorption of Cd, restored the damaged plasma membrane and chloroplast structure, improved the photosynthetic rate under Cd stress, and promoted the growth of aboveground biomass [16]