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Oncogene 43, 295303

Water Res , 37(8):197682

Limitations of traditional mechanistic frameworks Traditional models of CVD-cognitive impairment comorbidity primarily focus on vascular-mediated processes, including cerebral hypoperfusion, where arterial stenosis or HF-induced reduction in blood flow impairs the delivery of oxygen and nutrients to neurons

This issue can trigger oxidative stress, making life tough on our cells and tissues

Diabetes (2008) 57(2):4519

It may be important to include measurements of biomarkers of oxidative damage (e.g., products of DNA and lipid oxidation, such as 8-hydroxy-2-deoxyguanosine, 8-OHdG, or F 2 -isoprostanes) in observational studies, suggesting that the therapeutic benefit may actually be associated with an antioxidant effect (Moosmann and Behl, 2002