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Each of these pathways plays a critical role in regulating appetite, energy expenditure, fat metabolism, and glucose control

3 Compared with standard L-dopa therapy, some researchers recommend the initiation of a COMT inhibitor at the onset of L-dopa therapy to reduce the risk of developing motor complications

Net result : no systemic 5AR inhibition even with a 5mg injection

62, 1510S1516S

Dumbrava EEI, Pinchasik D, Damodar S, Hess K, Pairawan SS, Moore J Hong DS, Janku F, Rodon J, Piha-Paul SA, Murthy R, Tapia C, Litton J, Luna K, Stuckett AS, Ferari D, Andreeff M , Tripathy D, Aivado M, Meric-Bernstam F

doi: 10.1038/nri3399 29 XueRZhangQCaoQKongRXiangXLiuHet al