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In vitro studies have shown that certain flavonoids, at high concentrations, can inhibit the growth of probiotic bacteria such as Lactobacillus app., while promoting the proliferation of opportunistic pathogens and inducing the accumulation of harmful metabolites, including H 2 S and NH 3 (Pan et al., 2023), which may adversely affect gut microbial homeostasis under specific conditions

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Precision therapeutics for inflammatory bowel disease: advancing ROS-responsive nanoparticles for targeted and multifunctional drug delivery

System Xc (SLC7A11 and SLC3A2) is critical for maintaining intracellular cysteine levels

Studies from multiple independent groups across musculoskeletal injury, gastrointestinal disease, vascular injury, and neurological insult have reported positive outcomes

Reversibility of age-related oxidized free NADH redox states in Alzheimer's disease neurons by imposed external Cys/CySS redox shifts