cdk4 glutathione MYC induces CDK4/6 inhibitors resistance by promoting pRB1 degradation Identification and inhibition of the
Identification and inhibition of the Cyclin D Rb docking interface that drives cell division bioRxiv Cyclin D Cdk4,6 drives cell cycle progression via the retinoblastoma protein's C terminal helix bioRxiv Discovery of the GSH responsive Y PROTACs targeting ALK and CDK4 6 as a potential treatment for cancer ScienceDirect CDK2 and CDK4: Cell Cycle Functions Evolve Distinct, Catalysis Competent Conformations, Offering Drug Targets JACS Au Addressing delivery and resistance issues of CDK4 6 inhibitors as cancer therapeutics ScienceDirect Targeting CDK4 6 for Anticancer Therapy
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