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To explore the role of PPARa in regulating FSP1 in vivo, we established PPARa over-expression and knockdown models in mice by intraspinal injection of lentivirus (Fig S3b, c)

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pmid:3858822

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6.1 Optimization of formulations and bioavailability Despite numerous delivery innovations, enhancing the bioavailability and retention of curcumin in oral tissues continues to be a priority