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In the usual course of things, a promising drug candidate would be ushered into human trials

215 In conclusion, suppression of the cGAS-STING pathway can be used to delay cell senescence and aging-related diseases

In addition, lipopolysaccharide (LPS) and D-galactosamine (D-GaIN-)-induced liver injury is a widely used preclinical model of ALF

The pirfenidone 2400-mg group had an intermediate change in eGFR ( 1.9 6.7 ml/min per 1.73 m 2 ) that was not significantly different from that of the placebo arm [221]