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eCl 2016;4:31-5

In the context of treating TAO, caffeine appears to inhibit orbital changes by reducing ROS production in response to cellular oxidative stress and exhibiting anti-adipogenic effects (159)

Gastroenterology (2021) 160(2):52437

The dosage and frequency of sessions can vary depending on an individuals skin tone.

With prolonged exposure or high doses, it transitions to a Phase II block, involving both pre- and post-synaptic effects, including impaired acetylcholine release (autoreceptor inhibition) and open-channel block