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Such patterns point to the potential of regional KP activity as a functional biomarker for stress-related symptom dimensions in MDD and highlight localized KP enzymes such as IDO, TDO, and kynureninase as candidate treatment targets

The impact of TGF-beta on lung fibrosis: from targeting to biomarkers

Within the islet, extracellular insulin inhibits glucagon secretion from alpha cells, while glucagon enhances both insulin and somatostatin secretion [93]