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vascular endothelial growth factor, basic fibroblast growth factor, and platelet derived growth factor)

The induction of the antimicrobial peptide gene expression is mostly initiated by binding of transcription factors like NF- B, AP-1, and STAT3 [26] due to activation of Toll-like receptors by microbial antigens or initiated by cytokines [27]

DSIP is ideally taken before bedtime to achieve optimal effects, distinguishing it from traditional sleep aids