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When foods containing B 12 are eaten, the vitamin is usually bound to protein and is released by proteases released by the pancreas into the small bowel

These symptoms can indirectly affect body weight because low energy often reduces appetite and activity

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The statistical analysis of the lipophilic fraction (Fig 2B and B) generated a weak OPLS-DA model with only limited class separation (with parameters R 2 = 0.56 and Q 2 = 0.28, CV-ANOVA test, P = 0.6), with a single metabolite (glycerophospholipidssphingomyelin) responsible for the class distinction (Figs 2B, B, and C and S3)