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Interestingly, the common findings from these studies demonstrated a high sensitivity of the spleen with respect to LDR-induced effects that are not similar to those found in other tissues, such as brain, liver, lung, and testis

investigated putative role of melatonin in alleviation of ifosfamide induced nephrotoxicity in an animal study that involved the biochemical and histological considerations.86 Ifosfamide 50mg/kg for 5 days induced the GSH depletion and severe lipid peroxidation, myeloperoxidase activity, fibrosis which implied the marked oxidative stress and neutrophil infiltration

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High-sugar diets cause insulin spikes and inflammation, which further disturb hormonal balance and may lead to hair loss

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