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Base-called fast5 nanopore direct RNA sequencing data have been deposited at ENA under the accession PRJEB61652

Although transcriptomics and metabolomics provide valuable insights, experimental validation through in vivo functional studies is limited

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In a pilot study in Thailand, Sangsuwan and Asawanonda tested the influence of daily intake of oral collagen (5 g) for 4 weeks on skin elasticity, especially in sun-exposed areas, in a randomized, double-blind, placebo-controlled trial (in a total of 36 women, aged 4060 years, where one-half of the participants were in the treatment group [ n = 18] or the placebo group [ n = 18]) [39]

Depictions of adduct structures were generated using PyMOL (version 2.4.0) 31

"A varying degree"