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Moreover, energy insufficiency appears to prime immune activation, leading to increased proinflammatory responses to primary insults

Direct in situ measurement of nitric oxide in mesenteric resistance arteries

Cells were subsequently lifted from the plates, resuspended in PBS and divided into aliquots that were stained with BODIPY C11, MitoCLOX or CM-H2DCFDA for 15 min in a humidified tissue culture incubator (37 C, 5% CO 2 )

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Body composition may influence dosing requirements, though weight-based dosing has not been consistently employed in animal studies or limited human applications

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