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Therapeutic Approaches for Protecting the BBB by Inhibiting Oxidative Damage Antioxidants play a crucial role in protecting BBB integrity by counteracting the damaging effects of oxidative stress [143,196,205]

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doi: 10.21147/j.issn.1000-9604.2017.03.10 8 CavalloFDe GiovanniCNanniPForniGLolliniP-L

Patients improved on both sensation tests and neuropathy scores, and no side effects were reported (Ebadi et al., 2023)

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For example, the release of interleukin-1 in murine rectal cancer models caused the differentiation of tumor-associated fibroblasts into more pro-tumorigenic fibroblasts and reduced the anti-tumor effect of radiotherapy (107)