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These studies showed that adding probiotics to conventional medications for coronary artery disease reduced the levels of low-density lipoprotein cholesterol, fasting glucose, and hypersensitive C-reactive protein and increased the levels of high-density lipoprotein cholesterol and nitric oxide ( An ongoing open-label, randomized, controlled clinical trial (Chinese Clinical Trials Registry ChiCTR2000038797) involving 2,594 adult patients diagnosed with acute myocardial infarction aims to assess the effects of probiotics on in-hospital mortality and the incidence of major adverse cardiovascular events

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Bidre N et al (2003) Cathepsin D triggers bax activation, resulting in selective apoptosis-inducing factor (AIF) relocation in T lymphocytes entering the early commitment phase to apoptosis

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Given the emergence of COVID-19 in the second year of the study, trial visits were permitted to be conducted via telephone, during which counseling was provided and safety-related information was collected