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Adams DJ, et al

A randomized, double-blind, placebo-controlled, parallel-group, multi-center trial comparing the effects of orally administered Xyrem (sodium oxybate) with placebo for the treatment of fibromyalgia [abstract]

Stripped of any IGF-1 triggers, it lets scientists study how cells break down stored lipids and channel energy, all in tightly controlled adipocyte and metabolic assays

Consistent use often leads to faster effects

Both OHCbl and CNCbl are frequently used for supplementation

These findings underscore the potential involvement of NNMT in lipid metabolism regulation and its relevance to the development of hyperlipidemia, a key component of MetS (Zhu et al., 2016)