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doi: 10.1002/med.22064 169

Fox Foundation Trial Finder, 43 the Washington PD Registry, 44 ClinicalTrials.gov (NCT02324426), and referral from local health-care providers

El-Dakroury WA, Zewail MB, Asaad GF, Abdallah HMI, Shabana ME, Said AR, Doghish AS, Azab HA, Amer DH, Hassan AE, Sayed AS, Samra GM, Sallam A-AM

This issue is further intensified by mitochondrial dysfunction, which impairs energy production and increases the creation of ROS

Membrane damage during ferroptosis is caused by oxidation of phospholipids catalyzed by the oxidoreductases POR and CYB5R1

Additionally, extended and chronic rotenone injections in LRRK2 transgenic mice lead to DA neuron degeneration in the SN pars compacta and striatum, along with -syn aggregation and the development of PD-associated dyskinesia (Ng et al