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Treatment effect estimation For each tested drug, we estimated drug treatment effect for each balanced trial by calculating the hazard ratio (HR) using a Cox proportional hazard model 102 , comparing the risk to develop a specific outcome between the treated and control groups

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A shunt counts the actual energy flowing in and out (Coulomb counting), which is far more accurate than voltage sensing alone

Overall, the lipid profile in PCOS is frequently mixed/atherogenic, with variability according to obesity, IR, hyperandrogenism, and genetic/familial predisposition, highlighting the importance of early screening and longitudinal monitoring for CV risk [388] Table 10

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