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These results indicated that the disturbed profile of plasma metabolites was strongly associated with the altered concentrations of cytokines and chemokines, implying that altered metabolic profiles might affect the pathogenesis of MS by modulating the immuno-inflammatory responses in the peripheral system

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A total of 177 natural products with greater potential for AD treatment were screened by mapping the target gene set of each natural product to the constructed network, yielding 177, 103, and 29 natural products from Most Studied Pathways, Gene-Associated Pathways, and Popular Pathways, respectively (Additional file 1: Table S7)