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It should be noted that GCLM KO mice have systemic GSH deficiencies, ranging from 10 to 40% of normal levels depending on the tissue type 16

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The few subcellular fractionation datasets that are available have been suggestive of only minor NADP redox changes at dark-light changes in the cytosolic fractions, which appears in stark contrast to pronounced NADP redox dynamics in the chloroplast, and indeed NAD redox dynamics in the cytosol 36,37,38

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All NAPstars showed some affinity to NADH, titrated in the presence of 500 M NAD + , with K d(NADH) ranging from 24.4248.9 M