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FIGURE 1 3.2 Oxidative stress markers, H 2 S level and mtNOS activity in heart mitochondria in glutathione-treated old rats It was shown that in old rat heart mitochondria, the values of oxidative stress indicators such as generation rates of O 2 and H 2 O 2 as well as the content of the primary products of lipid peroxidation products (DC and MDA) were higher in heart mitochondria of old rats comparing to adult ones (Table 2) indicating aggravation of free radical processes with age

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Each stack pairs compounds with distinct but synergistic pathways expanding the research scope beyond what single peptides can achieve

The high expression of TDO2 is a key driver of TLS maturation defects