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Glossary Satellite cells A population of muscle stem cells that are committed to the myogenic lineage and normally reside in a quiescent state at the surface of fully differentiated muscle fibres

& Paegel, B

Wang, W., Mou, Y., Lu, D., & Xu, S

In this review, we deconstruct cancer therapy resistance using the conceptual framework of the epigenetic landscape. We summarize the molecular functions and crosstalk among the major epigenetic layers and describe how this integrated network sustains key resistance-associated phenotypes

The most parsimonious hypothesis is simply that this is a case of a viral protease targeting a cellular gene for cleavage, for which there are abundant precedents, including the proposed M pro targeting of TRMT1 and HDAC2 ( Functional Effects of M PRO in Transfected Cells are Consistent With GPX1 Knockdown As detailed above, the original 2003 SCoV M pro has essentially identical substrate sequence specificity as that of SCoV2

10.1161/01.res.87.9.746 121