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Practical Take-Home Points Prochlorperazine IV and GONB are must-offer therapies Metoclopramide remains appropriate when prochlorperazine is unavailable Dexamethasone may be used for acute treatment, beyond recurrence prevention Opioids should be avoided References Orr SL, Friedman BW, Christie S, et al

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Early life stress alters the developmental trajectory of corticolimbic endocannabinoid signaling in male rats