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Others lose potency as they pass through digestion

Studies have shown SAD affects women four times more than men

This is why a minor stressor can trigger a massive symptom flare-up years later [6]

Weeks 3-8: 300 mcg daily, 5 days on / 2 days off

& Wolfram, J

Furthermore, a different approach using intragastrically administered rotenone (5 mg/Kg) in mice showed that the accumulation and aggregation of -synuclein in neurons of the dorsal motor nucleus of the vagus (DMV) and the intermediolateral nucleus (IML) in the spinal cord was accompanied by the selective loss of dopaminergic neurons and astrogliosis, suggesting that the gastric administration of rotenone through the connection of the enteric nervous system (ENS) with anatomical structures of the CNS also induces PD-like features [11,19]