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Two classes of ferroptosis-inducing compounds were investigated (Fig

Ramalingam, S

10.1016/s0006-8993(01)02870-0 222 MancusoR.Del ValleJ.ModolL.MartinezA.Granado-SerranoA

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This fundamental relationship implies that partial v-ATPase inhibition might be beneficial in specific conditions of mitochondrial dysfunction with relevance beyond primary mitochondrial disorders, including neurodegenerative diseases (e.g., lysosomal storage diseases), cancer and ageing

The dysbiosis would also lead to disruptions in the immune function, which contributes to post-infections in IBS patients which could become chronic