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Side-effects were of similar severity in asthmatics and nonasthmatics

These observations point to a global reprogramming of circadian gene expression, rather than a disruption that may confer a physiological advantage to tumor cells and prompt to suggest that clock dysfunction could be considered a pro-tumoral event, thus indicating clock dysfunction as a potential hallmark of cancer

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Some patients may experience mild redness, tenderness, swelling, or bruising at the injection sites, but these effects are typically temporary