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How best to manage patients with chronic lymphocytic leuekmia with 17p deletion and/or TP53 mutation

applied patient-derived liver-on-chips and human liver organoids to model and predict DILI risk, which was assessed by ALT, AST, albumin, microscopy-based morphological profiling and single-cell sequencing

The direct functional link of BRCA1 and BRCA2 to the DNA damage response was first demonstrated [132, 133]

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