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By leveraging complex computational models, machine learning techniques, and large datasets, artificial intelligence algorithms can efficiently analyze the vast space of peptide sequences and structures, predicting their potential anti-cancer activity and identifying optimal candidates for further experimental validation

In addition to direct modulators, phosphorylation inhibitors, which target tau aggregation by reducing the hyperphosphorylation that correlates with aggregation, have been tested as potential therapeutic agents, yet to date, none of the attempts have resulted in approved therapy

Loss of function in the encoded transporters results in impaired biliary cholesterol efflux, clinically recognized as sitosterolemia

This association persisted for at least 48 h post transformation from miracidia to sporocyst, suggesting the developing larvae consistently share at least certain surface proteins during the first 48 h of infection, during which, they are most likely to be targeted by the snail immune response (28)

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Khan MN, Lane ME, McCarron PA, Tambuwala MM