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Ferroptosis is a regulated form of cell death characterized by iron dependency, lipid peroxidation, and oxidative stress [19, 20]

Sci Rep (2021) 11(1):14987

N-acetylcysteine in the treatment of craving in substance use disorders: systematic review and meta-analysis

[DOI] [PMC free article] [PubMed] [Google Scholar] Geeganage, J

it showed that risk rises with long-term high Lp(a).[ref] Waist-to-hip ratio as a modifying factor for atherosclerosis: A 2025 study involving ~800 people with Lp(a) over 50 mg/dL showed that those with a larger waist-to-hip ratio (more belly fat) were at a much higher risk of atherosclerosis

The link likely involves chronic inflammation, oxidative stress from poor glucose control, and microvascular complications affecting multiple organs including bone marrow