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Current status of treatment of acute leukemia in adults: an overview of the Memorial experience and review of literature

339 ZhangMet al

Copper binds to and inhibits protein tyrosine phosphatase N2 (PTPN2), leading to the loss of its phosphatase activity

Notably, the dual nature of copper imbalanceboth deficiency and excesscontributes to cardiovascular damage via distinct yet interconnected pathways

The strong association between sleep-related impairment and self-reported fatigue severity suggests that the increased fatigue in the +ADT group may be due to sleep dysfunction