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Biosynthesis of 25hydroxycholesterol in macrophages is stimulated by the endotoxin Kdo2-lipid A, the component of the lipopolysaccharide present on the outer membrane of Gram-negative bacteria, which acts as an agonist for Toll-like receptor 4 (TLR4)

Ethanol induces fatty acid synthesis pathways by activation of sterol regulatory element-binding protein (SREBP)

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