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Med Princ Pract 29(4):364370

Finally, a number of inherited mutations in genes involved in carnitine shuttling and fatty acid oxidation pathways do not systematically result in carnitine depletion (such that carnitine supplementation may not help mitigate the symptoms) but lead to abnormal profiles of acylcarnitine esters in blood (35, 40)

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Often used as a layered approach

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Miller recommends always applying glycolic acid in the morning (followed by a moisturizer and sunscreen or as a combination product) and retinol at night