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It is not possible to reliably determine whether T291 or T292 are phosphorylated by LRRK2 as alanine mutations of one site most likely impact the phosphorylation motif of the other site, whereas definitively resolving phosphorylation sites between adjacent identical residues (i.e., pTT or TpT) in a single phospho-peptide by mass spectrometry is not possible

Prior to the meeting, more than a half-dozen people with connections to the peptide industry were added to the panel, including doctors, pharmacists or consultants who work in the field

Prior to initiating the experiment, these fish were fed a control diet twice daily

Tasks that felt overwhelming can feel more manageable

Santos-Morales O, Daz-Machado A, Jimnez-Rodrguez D, Pomares-Iturralde Y, Festary-Casanovas T, Gonzlez-Delgado CA, et al

Banxia xiexin decoction protects against dextran sulfate sodium-induced chronic ulcerative colitis in mice