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4123-A SERUM LEVELS OF CIRCULATING SOLUBLE B- AND T- LYMPHOCYTE ATTENUATOR IN UNRESECTABLE HEPATOCELLULAR CARCINOMA AS A PREDICTOR OF RESPONSE TO ATEZOLIZUMAB AND BEVACIZUMAB Naoshi Odagiri, Hoang Hai, Le Thi Thanh Thuy, Yoshimi Yukawa-Muto, Kohei Kotani, Hiroyuki Motoyama, Ritsuzo Kozuka, Etsushi Kawamura, Atsushi Hagihara, Hideki Fujii, Sawako Uchida-Kobayashi, Masaru Enomoto and Norifumi Kawada, Osaka Metropolitan University Graduate School of Medicine Background: Atezolizumab and bevacizumab (Atezo+Bev) therapy is widely used as a first-line drug for unresectable hepatocellular carcinoma (HCC)

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Immunity, tolerance and autoimmunity in the liver: a comprehensive review