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For example, higher expression of ABCB1 results in resistance to widely used anti-cancer Aurora Kinase Inhibitor (GSK-1070916) in colon cancer cells [332]

In obesity and insulin resistance, mitophagy markers, including LC3BII, Parkin, FUNDC1, and BNIP3, are generally reduced in both human and animal studies, reflecting compromised mitochondrial turnover

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Dietary doses may antagonize normal cancer treatments by counteracting with OS which is required to kill cancer cells during radio- and chemotherapy